Season 15 • Episode 6
Hot Shots
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2016-11-13
★ 6.5
22 min
In order to "save" Stewie from autism, Peter and Lois decide not to vaccinate him and then proceed to convince the rest of Quahog to follow suit. Stewie runs away to save himself from diseases until Sean Penn swoops in to save the day and brings vaccines to the whole town.
Guest Stars
Hopper Penn
Sean Penn
Jerry Lambert